M22

M22 is a cryoprotectant that the Alcor Life Extension Foundation uses in vitrification. M22 was developed by 21st Century Medicine. M22 replaced B2C, a vitrification solution that Alcor had used until 2005. The name of M22 refers to minus 22 degrees Celsius, which is the temperature at which the full-strength solution is perfused into kidneys in published organ cryopreservation experiments.

M22 concentrate for whole-body preservation and M22 concentrate for neuropreservation are not the same. M22 concentrate for whole body patients has an additional component to mitigate edema during perfusion.

The first person vitrified with M22 is A-2071, a whole-body patient who was cryopreserved by Alcor in August 2005. A-1598, who was cryopreserved in October 2005, is the first neuropreservation patient vitrified with M22.